Too often, preclinical successes are followed by clinical failures. And all clinical failures hurt. Perhaps the most painful failures occur in trials that require large patient populations and long ...

Animal models are established, important tools for preclinical safety and efficacy testing. Companies are advancing more “humanized” models to better reflect human responses, while at the same time ...

Preclinical testing is vital for assessing the safety profiles and potential efficacy of new therapeutics in development. Animal testing is one of two routes usually selected for the preclinical stage ...

Torie Bosch is the First Opinion editor at STAT. First Opinion is STAT’s platform for interesting, illuminating, and provocative articles about the life sciences writ large, written by biotech ...

Animal testing remains to be a vital part of modern preclinical testing. While the ethics of the use of animals in medical testing remains keenly debated, it is still generally accepted worldwide and ...

"Rodents are the most widely utilized models in biomedical research...The majority of oncology drugs that proved successful in treating tumors within rodents fail to have the same response in humans, ...