Breast cancer development is not solely the result of cancer cells acting independently, it involves a dynamic and complex ecosystem composed of cancer cells, immune cells, fibroblasts, adipocytes, ...
FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...
Head and neck cancer remains a major global health challenge, ranking among the six most common cancers worldwide and claiming hundreds of thousands of lives each year. A growing body of evidence now ...
The study of metabolism within the tumour microenvironment (TME) is a rapidly evolving field that holds significant ...
HER2-positive gastric cancer accounts for a substantial proportion of advanced cases and has long been treated with HER2-targeted therapies. While trastuzumab deruxtecan has shown superior activity ...
Immunometabolism has emerged as a central hub linking infection, inflammation, cell death, and cancer. The metabolic state of cells profoundly shapes their ...
Hyeyoung Nam, Ph.D., professor in the UAB Department of Urology, has been published in Science Advances alongside corresponding author, Sunil Sudarshan, M.D. and colleagues Richard L. Kirkman and ...
A key molecular mechanism drives the growth of liver cell cancer while simultaneously suppressing the body's immune response ...
A novel study using a mouse model has found that the absence of the angiopoietin-like 4 (ANGPTL4) protein during development ...
Tumor growth unfolds within a tumor microenvironment (TME) defined by metabolic–immune crosstalk. Emerging evidence indicates that cancer cells not only reprogram glycolysis but also alter amino acid, ...
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