No gene acts alone: interacting variants and protein partnerships can worsen, mask or even rescue disease risk, demanding ...
A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most ...
DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave. Researchers have now mapped this hidden architecture in unprecedented detail, showing ...
In mantle cell lymphoma (MCL), an aggressive form of B-cell non-Hodgkin lymphoma, TP53 mutations are known to affect patients’ prognosis—but questions remain. What does the heterogeneity of TP53 ...
A new study led by Aaron Hobbs, Ph.D., and Rachel Burge, Ph.D., at MUSC Hollings Cancer Center, reveals why a specific gene ...
A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the ...
Scientists at Duke-NUS Medical School and the National University Health System (NUHS), together with an international team ...
After years of studying genes that increase risk for Alzheimer’s disease, scientists report the promising discovery of DNA that does the opposite: the first gene variant that protects people against ...