GEN - Genetic Engineering and Biotechnology News

DNA-Protein Crosslinks Drive Inflammation Linked to Early Aging

A new mouse study found that unrepaired DNA-protein crosslinks activate inflammatory signaling pathways that trigger early aging disorders.
EurekAlert!

A single-site DNA–histone cross-link causes a global breakdown of nucleosome structure and function

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...
News-Medical.Net on MSN

COVID-19 severity is linked to changes in mitochondrial DNA methylation

By Tarun Sai Lomte New evidence from Indian patients shows that severe COVID-19 is associated with distinct mitochondrial ...
News-Medical.Net on MSN

Research reveals a link between defective DNA repair and immune-driven inflammatory disease

Unrepaired DNA-protein crosslinks (DPCs) – highly toxic tangles of protein and DNA – cause a process that leads to premature ...