The immune cell repertoire is composed of many different cell types that are orchestrated in response to infection and other pathogens that enter the body. As a result, the body can defend itself ...

MHC class II molecules are central to the adaptive immune response, serving as the means by which antigen-presenting cells, notably dendritic cells, display processed peptides to CD4+ T cells. This ...

NUFIP1 in Sepsis: Regulating Immune Function and Organ Dysfunction. This illustration demonstrates the pivotal role of NUFIP1-mediated ribophagy in dendritic cell activation and sepsis-induced immune ...

EPFL researchers have successfully engineered cells of the immune system to more effectively recognize cancer cells. The work, covered in two papers, turns the previously lab-based method into a ...

Immunotherapy has transformed healthcare and how physicians treat patients. Various forms of immunotherapy have been developed over the last two decades to target solid tumors and hematological ...

Cancer immunotherapy transforms a patient’s immune cells into a “search‑and‑destroy” force against tumors. But many cancers learn to camouflage themselves from dendritic cells—the immune system’s ...