For the Liu Lab, necessity is truly the mother of invention. The researchers were examining how the 3D organization of the ...

A new advance overcomes present limitations in spatial transcriptomics with a DNA nanotechnology-driven method called 'Light-Seq.' Light-Seq allows researchers to 'geotag' the full repertoire of RNA ...

Barcodes work based on light reflected back to scanner optics: black does not reflect light, while the white (blank) spaces do reflect light. Because characters (alphabetic, numeric, special) are ...

A new spatial transcriptomics technology—the DNA nanotechnology-driven method called “Light-Seq”—allows researchers to “geotag” the full repertoire of RNA sequences with unique DNA barcodes exclusive ...

To marvel at the choice and convenience of modern shopping, go visit your grocery-store mustard aisle. My local Whole Foods sells more than 20 different kinds: basic yellow mustard and Grey Poupon, ...

Janelia researchers developed an innovative new technique – cycleHCR -- that uses a novel DNA barcode system to track hundreds of RNA and protein molecules in single cells within thick biological ...

The initial round of imaging uses three barcodes, picking up three RNA molecules in three different colors. These barcodes are removed, and a second round of imaging uses three different barcodes and ...