CRISPR promises revolutionary cures, but its edits aren’t always perfect. To tackle hidden risks, UC San Diego researchers developed the ICP system, which fingerprints genetic edits and shows how they ...
Researchers at Forschungszentrum Jülich and Heinrich Heine University Düsseldorf have developed a tool that could significantly transform genome research: Helixer identifies genes directly from DNA ...
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Web-based tool improves CRISPR accuracy by identifying off-target effects across genetic variations
Genome editing technologies like CRISPR-Cas9 have transformed biology, medicine, and agriculture, but concerns remain about unintended edits at off-target DNA sites. These off-target effects can cause ...
Understanding the genetic mechanisms linking genome variations, such as single-nucleotide polymorphisms (SNPs), to phenotypes is challenging. Quantitative trait loci (QTLs) are genomic loci that ...
A collaboration including Rice University, Baylor College of Medicine and Texas Children’s Hospital’s Jan and Dan Duncan Neurological Research Institute (NRI) has produced a breakthrough in how to ...
When 18 individuals with overlapping symptoms were left without a unifying diagnosis, Yale’s Saquib Lakhani and Lauren Jeffries joined forces with researchers around the world to discern the genetic ...
(THE CONVERSATION) Mental illness is a growing public health problem. In 2019, an estimated 1 in 8 people around the world were affected by mental disorders like depression, schizophrenia or bipolar ...
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