Borrelia burgdorferi, one of the bacteria species causing Lyme disease, has a small genome and is therefore highly dependent on its hosts to obtain many necessary metabolites. Its small genome makes B ...

After so many years of learning how microbes work, researchers are now digitally recreating their inner workings to tackle challenges ranging from climate change to space colonization. In my work as a ...

TP53 Y220C mutations in advanced urothelial bladder cancer (UBC): A genomic landscape study. This is an ASCO Meeting Abstract from the 2025 ASCO Genitourinary Cancers Symposium. This abstract does not ...

Metabolic and regulatory networks may be expanded by coupling high-throughput phenotyping and gene expression data with the predictions of a computational model. (Reprinted with permission, Nature, ...

Scientists have developed a genome-scale metabolic model or 'subway map' of key metabolic activities of the bacterium that causes Lyme disease. Using this map, they have successfully identified two ...

A new approach to treating inflammatory diseases through personalised probiotic therapies -- also known as precision medicine -- has been proposed by researchers. A new approach to treating ...