Germ cell development and oogenesis represent central processes in the reproduction of invertebrates, exhibiting remarkable diversity in cellular architecture, developmental mechanisms and functional ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

In human cells, DNA carries chemical or "epigenetic" marks that decide how genes will be used in different tissues. Yet in a ...

In our cells, our DNA carries chemical or 'epigenetic' marks that decide how genes will be used in different tissues. Yet in the group of specialised ...

Germ cells pass DNA to the next generation and undergo massive reorganization of their DNA packaging to generate totipotency, or the ability to differentiate into any cell type. Understanding the ...

Researchers at the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have shown for the first time that, before they can start developing into egg and sperm cells, the embryonic ...

The new method offers researchers a powerful new platform to investigate the molecular mechanisms that control oogenesis, the process by which egg cells develop, and lays important groundwork for ...