During drug development, researchers need to perform adequate nonclinical testing to ensure a drug’s safety and efficacy before starting clinical trials. An important aspect they must evaluate is a ...

Inflammatory bowel disease (IBD) is a major global health concern, with an estimated 1.6 million cases in the US alone. While there are many treatments available, they are often ineffective and can ...

A research team led by the Medical University of Vienna and the University of Vienna has investigated a possible link between ...

Thanks to lab-grown miniature intestines, researchers at Uppsala University have successfully mapped how aggressive Shigella bacteria infect the human gut. The study opens the door to using cultured ...

Thanks to lab-grown miniature intestines, researchers at Uppsala University have successfully mapped how aggressive Shigella bacteria infect the human gut. The study opens the door to using cultured ...

Infectious microbes have evolved sophisticated means to invade host cells, outwit the body’s defenses and cause disease. While researchers have tried to puzzle out the complicated interactions between ...

The intestinal epithelium undergoes rapid renewal every 3–5 days, a process driven by intestinal stem cells (ISCs) located at the base of crypts. While ISCs play an essential role in epithelial ...

Intestinal pseudo-obstruction is a rare condition that occurs when you have symptoms of intestinal obstruction without anything physically blocking the intestines. It can be chronic or develop ...