Physician's Weekly

Interpreting Extreme Lactate Levels: Why Clinical Context Matters

Blood lactate is influenced by a wide range of metabolic processes. Blood lactate—much like central venous pressure—can ...
Physician's Weekly

Clarifying a Common Critical Care Lab Test: Blood Lactate

COOH) represents the protonated form of the organic acid, whereas lactate (CH₃CH (OH)COO⁻) represents its conjugated base.
Medscape

Elevated Lactate Dehydrogenase Levels Predict Worse Outcomes in Heart Failure With Reduced Ejection Fraction

Elevated baseline LDH levels predict worse clinical outcomes in heart failure with reduced ejection fraction and modestly ...
Case Western Reserve University

Lactate Metabolism, Signaling, and Function in Brain Development, Synaptic Plasticity, Angiogenesis, and Neurodegenerative Diseases

Abstract: Neural tissue requires a great metabolic demand despite negligible intrinsic energy stores. As a result, the central nervous system (CNS) depends upon a continuous influx of metabolic ...
ascopubs.org

Pretreatment levels of serum lactate dehydrogenase (LDH) and clinical outcome in metastatic colorectal cancer patients receiving first-line chemotherapy and bevacizumab.

The single-nucleotide polymorphism T>C rs4353229 in CASP7 gene and mir-224 as new biomarkers of oxaliplatin-induced neurotoxicity in advanced colorectal cancer. Background: No predictive marker for ...
ascopubs.org

Serum lactate dehydrogenase (LDH) changes during sunitinib treatment in patients with renal cell carcinoma (RCC)

Cost effectiveness of zoledronic acid in the prevention of skeletal related events in renal cell carcinoma patients with bone metastases: An exploratory analysis for France initial level of LDH ...