Researchers have mapped the spatial distribution of around 700 long non-coding RNAs, otherwise known as lncRNAs, in the testes. The team discovered much higher levels of lncRNAs in the testes than had ...

In the post-genomic era, long non-coding RNAs (lncRNAs) have emerged as critical regulators in various cancers and hold potential as minimally invasive diagnostic biomarkers. This study aimed to ...

Long non-coding RNAs (lncRNAs) represent a diverse class of transcripts that, despite lacking protein‐coding capacity, play critical roles in the regulation of gene expression. Their functions span ...

Schematic representation summarising MASLD-associated long non-coding RNAs (lncRNAs) and their relevant targets in hepatocytes: human leukocyte antigen (HLA) complex group 18 (HCG18), nuclear enriched ...

The human genome contains about 20,000 protein-coding genes, but that only accounts for roughly two percent of the genome. For many years, it was easier for scientists to simply ignore all of that ...

When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...

A sum of 921 samples were collected from three independent data sets. We obtained pyroptosis-related genes from both the Molecular Signatures Database and relevant literature sources and used four ...

Contrary to historic understanding of RNA’s longevity in cells, some RNAs can persist in cells throughout the life of an organism. Lead authors, Martin Hetzer, PhD, president of the Institute of ...

Research in Aging Cell indicates that blood levels of particular small non-coding RNAs, which regulate gene expression, may ...