Mast cell leukemia (MCL) is a quick-progressing condition that leads to the buildup of mast cells in your bone marrow and other tissues. It falls into a group of diseases collectively known as ...

Mast cell activation syndrome (MCAS) is a condition that occurs when the mast cells in your body release too much of a substance that causes allergy-like symptoms. Mast cells are part of your immune ...

Mast cells develop from hematopoietic progenitors in response to stem-cell factor (KIT ligand), which is the ligand of the CD117 transmembrane tyrosine kinase receptor, encoded by KIT. CD117 regulates ...

Mast cells are a type of innate immune cell. They contain large granules that are packed with immunomodulatory and vasoactive molecules, which are released following mast cell degranulation. Mast ...

A rare set of immune diseases called clonal mast cell activation disorders (cMCADs) may be associated with strong immunity to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is ...

For many patients with diverse and seemingly unrelated symptoms, obtaining an accurate diagnosis can take years of specialist visits and inconclusive tests. Mast cell activation syndrome, a disorder ...

The significant mortality rate associated with the ongoing Coronavirus disease 2019 (COVID-19) pandemic has been linked to acute respiratory distress syndrome (ARDS) and multi-organ dysfunction.

Mast cell activation syndrome, or disease (MCAS), is a condition that causes mast cells to release these substances too frequently, resulting in severe allergic reactions. After detecting an allergen, ...

Mast cell activation syndrome is a condition that causes mast cells to release an inappropriate amount of chemicals into your body. This causes allergy symptoms and a wide range of other symptoms.