Mast cells are pivotal effectors in immune responses, acting as both sentinels and mediators in allergic and inflammatory processes. Their ability to rapidly degranulate and release a myriad of ...

Eosinophils and mast cells are two types of immune cells with critical roles in responding to foreign assaults. When these cells do not function properly, several disease outcomes can develop (e.g.

Explore the link between histamine and migraine. Learn about histamine intolerance, acute treatments like Benadryl, and ...

(BPT) – Do you often get a skin rash after you are exposed to an allergen or irritant? Do you also develop breathing problems and stomach issues? Bone or muscle pain? You may want to learn about mast ...

Advanced systemic mastocytosis (advSM) is a rare and serious form of systemic mastocytosis, a blood disorder that involves the overproduction of mast cells. Mast cells are a type of white blood cell ...

New research at WashU Medicine has found that histamine-releasing immune cells cause the gates to the brain to close when bacteria are detected, blocking fluid movement out of the brain and pathogen ...

Barzolvolimab achieved sustained complete responses and improved quality of life in patients with CSU up to 76 weeks post-treatment. The therapy targets mast cells by inhibiting receptor tyrosine ...

In 2015, Marla Barkoff, MD, was a healthy mom and board-certified endocrinologist practicing at the University of Illinois Hospital in Chicago when a bunch of debilitating symptoms landed her on the ...