Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, No. 2 (Jan. 19, 1999), pp. 376-381 (6 pages) The mediator complex is essential for regulated transcription in ...

Enhancer sequences increase gene transcription with the help of a co-activator complex, the Mediator. Another protein complex — cohesin — seems to work with Mediator to bring together enhancers and ...

A new study advances existing knowledge about transcription and gene expression. This multi-institution team of researchers made interesting discoveries about the role of the Mediator protein complex ...

Researchers at Umeå University, Sweden, have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide. The discovery may be ...

The Pre-Initiation Complex (PIC), which consists of Mediator, TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH, and RNA polymerase II (RNAPII), governs the expression of all protein-coding and most non-coding ...

Did you know that the DNA in any cell of the human body - or any organism for that matter - contains the genetic information required to develop every possible type of cell within that organism? Yet ...