Large numbers of drug discovery projects involve the analysis of gene-expression levels to accurately assess target effects. When screening compounds from a library, it is common to use microarray ...

Enzymes play vital roles in biological systems, catalyzing practically every biological reaction and metabolic exchange 1. The substrate specificity is thus of utmost importance in governing the ...

As sequencing projects of microbial organisms are being completed, a large number of genes of potential biological and medical relevance are classified as 'unknown' because their unique sequence and ...

Predicting positive bone marrow biopsies (BMBs) in patients (PTS) with advanced prostate cancer (APC). This is an ASCO Meeting Abstract from the 2014 Genitourinary Cancers Symposium. This abstract ...

Protein microarrays are many things to many people. Like the more mature DNA “chips”, they are often patterns of tiny spots arrayed on a microscope-type slide, used to determine the makeup and amount ...

Scientific advances in the field of genetics and gene-expression profiling have revolutionized the concept of patient-tailored treatment. Analysis of differential gene-expression patterns across ...

The Microarray Innovations in Leukemia study assessed the clinical utility of gene expression profiling as a single test to subtype leukemias into conventional categories of myeloid and lymphoid ...