RNA drugs are the next frontier of medicine, but manufacturing them requires an expensive and labor-intensive process that limits production and produces metric tons of toxic chemical waste.

A group of interdisciplinary Boston University researchers worked together to investigate the promising technology of self-amplifying RNA as a way to deliver lifesaving drugs and create more effective ...

Schematic representation of how self-amplifying RNA works. Despite the apparent success of Covid mRNA vaccines, fundamental issues remain. The limitations of the current Pfizer and Moderna vaccines ...

At the mRNA Health conference in Berlin, enginzyme and AGC Inc. presented a scalable process to produce a key mRNA vaccine and therapy ingredient, N1-methylpseudouridine-5'-triphosphate (m¹ΨTP).

A new paper published in Nature Biotechnology this week titled, “Template-independent enzymatic synthesis of RNA oligonucleotides,” provides details of a method for synthesizing single-stranded RNA ...

While the COVID-19 vaccines introduced many people to RNA-based medicines, RNA oligonucleotides have already been on the market for years to treat diseases like Duchenne Muscular Dystrophy and ...

Nucleotides are the fundamental units that make up the genetic material of all living organisms. They are the building blocks of DNA and RNA, which store and transmit genetic information. Nucleotides ...

While the COVID-19 vaccines introduced many people to RNA-based medicines, RNA oligonucleotides have already been on the market for years to treat diseases like Duchenne Muscular Dystrophy and ...