Stem cell researchers have uncovered for the first time why adult human cardiac myocytes have lost their ability to proliferate, perhaps explaining why the human heart has little regenerative capacity ...
Mst1 causes the transport of FoxO1 from the cell cytoplasm to the nucleus by phosphorylating it. This is shown by the colocalization of the green and the blue stain when Ad-Mst1 is added. Researchers ...
bit.bio has today launched a new product, ioSkeletal Myocytes. It’s the first product of its kind that provides physiologically relevant human skeletal muscle cells that are reliable, reproducible and ...
Tissue microenvironments can regulate cell behavior by imposing physical restrictions on their geometry and size. An example of these phenomena is cardiac morphogenesis, where morphometric changes in ...
During the development of hypertrophy, cardiac myocytes increase organization of the sarcomere, a highly ordered contractile unit in striated muscle cells. Several hypertrophic agonists, such as ...
The scarring of the heart tissue after a myocardial infarction suggests that the myocytes are unable to divide. In June 7 New England Journal of Medicine Antonio Beltrami and colleagues from the New ...