More than 85 years after the discovery of progesterone (P4) by Corner and Allen 1, we have limited understanding of its molecular role in pregnancy maintenance and the initiation of labour.

A single large fibroid may occupy the entire uterine fundus (Panel A, bivalved) and obliterate the endometrial cavity, but many fibroids of varying size can also grow in a single uterus (Panel B).

Doctor recommends approaching closure with the precision of plastic surgery ...

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