A new study in The Journal of Immunology reveals how a high-fat diet may impair the immune system's ability to respond to infection by impacting the function of neutrophils, one of the first immune ...

Researchers have examined cellular crosstalk between the gut and liver during sepsis, helping us better understand sepsis ...

Hospitalized older adults with community-acquired pneumonia (CAP) and sepsis exhibit impaired neutrophil function; however, glycolytic metabolism is not the driver of neutrophil dysfunction. This ...

Figure 1: Mechanisms involved in regulation of tumor progression by neutrophil PAD4. “Using several transplantable and genetically engineered mouse models, we demonstrated that tumor growth was ...

A more-developed version of the assay used in this study may help manage patients with acute decompensation of liver cirrhosis or acute-on-chronic liver failure before liver transplantation. Patients ...

In the daytime (left), neutrophils (green) accumulate in tissue bordering the initial site of injury caused by heart attack–induced oxygen deprivation (region surrounded by the dotted line). However, ...

The human body hates not getting enough oxygen. Without it, confusion takes over, breathing and heart rate change, and skin turns blue. It turns out that the immune system feels the effects of not ...

Neutrophils, one of the immune system warriors that were thought to be all the same, turn out to be diverse. Unfortunately, these cells are also active in autoimmune diseases. New research from Japan ...