In 1869, Swiss scientist Friedrich Miescher isolated a mysterious substance from cell nuclei—an overlooked finding that would ...

Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

A plethora of chemical or enzymatic methods are available to generate nucleic acids such as those labeled with fluorophores, enzymes and radioactive phosphates, or nucleotides modified with ...

To obtain high-quality, purified nucleic acids, scientists can use several different methods, including phenol-chloroform extraction, cesium chloride/ethidium bromide (CsCl/EtBr) gradient ...

An early clinical trial in individuals with the deadly brain cancer, glioblastoma, showed an experimental spherical nucleic acid (SNA) drug developed by Northwestern University scientists was able to ...

Nucleic acid technology came of age during COVID-19 with biopharma firms developing, testing, mass producing, and shipping mRNA vaccines in record time. However, as the pandemic ebbs, the industry now ...

The first drug using spherical nucleic acids to be systemically given to humans has been developed by Northwestern University scientists and approved by the Food and Drug Administration as an ...

Guanine quadruplexes (G-quadruplexes or G4s) are unusual nucleic acid structures with distinct biological and chemical functions. They have occupied significant attention in the nucleic acid world ...

A research team has found that compounds in the nucleic acids derived from food can inhibit the growth of certain cancer cells. When people eat, they ingest the nucleic acids that reside in all living ...

Dr. Chad Mirkin, Director of International Institute for Nanotechnology talks to News-Medical Life Science about the use of spherical nucleic acids (SNAs) in vaccinations and treatments for disease, ...