Scientists discover how the Fas-p53 pathway sabotages energy metabolism, offering new hope for tackling obesity and improving insulin sensitivity. Brief Communication: Expression of p53 in human ...
PURPOSE: To identify the role of p53 pathway alteration(s) as predictors of treatment outcome in patients with advanced, resectable, squamous cell carcinoma (SCC) of the larynx and pharynx treated ...
“Our results provide unique insights into the mechanism of action of PG3 as a novel cancer therapeutic targeting p53 pathway-like tumor suppression” As highlighted in the abstract of this study, ...
AZD1775 plays a role in the regulation of ferroptosis by dually targeting the cystine uptake and the WEE1-SETDB1 axis, while the activation of the p53-SLC7A11 cascade by Act. D augments ...
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