Telomere length and polygenic risk scores (PRS) are linked to idiopathic pulmonary fibrosis (IPF) risk, especially in noncarriers of rare genetic variants. The study identified rare damaging variants ...

Over a century after Mendel established the foundations of inheritance, genomics has revealed that most human traits and common diseases arise from the ...

23andMe Holding Co. has launched a new polygenic risk score (PRS) report for osteoporosis, available to 23andMe+ Premium members. This report assesses an individual's genetic likelihood of developing ...

Despite major advances in genetic testing for breast cancer risk prediction, death rates remain disproportionately high among ...

The addition of polygenic risk scores (PRS) improved the accuracy of the cardiovascular disease (CVD) risk prediction tool PREVENT across all groups studied, across ancestries. Over 3 million people ...

A polygenic risk score (PRS) based on genes associated with endothelial cell function identifies patients at a higher risk of coronary artery disease, according to a new study. The risk score, which ...

A polygenic risk score (PRS) may help identify women who are at a greater risk of developing a future breast cancer after treatment for in situ breast disease, a retrospective study suggests. The ...

Nearly all men with a polygenic risk score in the 90th percentile or above had a 10-year absolute risk for prostate cancer exceeding 3.8%. A polygenic risk score (PRS) identifies more patients with ...

Bottom Line: In a retrospective study, the 313-SNP breast cancer polygenic risk score (PRS 313) blood test could predict future incidents of breast cancer in women diagnosed with ductal carcinoma in ...

Cardiovascular disease ("CVD") is the leading cause of death in the US and worldwide with over 82 million Americans living with CVD. CVD accounts for one in every three deaths in the US, or more than ...