Telomere length and polygenic risk scores (PRS) are linked to idiopathic pulmonary fibrosis (IPF) risk, especially in noncarriers of rare genetic variants. The study identified rare damaging variants ...

Using twin data from TEDS, researchers compared polygenic score prediction within families and across the population. They found that about half of predictive power for cognitive and educational ...

Over a century after Mendel established the foundations of inheritance, genomics has revealed that most human traits and common diseases arise from the ...

The figure illustrates the major categories of genes that may influence susceptibility to dental caries, organized by their biological functions and pathways. These groups include: (1) Enamel ...

Please provide your email address to receive an email when new articles are posted on . Researchers said common risk variants help explain why epilepsy occurs in some family members and not others.

Cancer is challenging to treat, yet identifying individuals with greater risk of developing disease can assist with early detection and increased treatment efficacy. There are several types of risk ...

The optimism is not unfounded. In specific, well-defined clinical scenarios, polygenic scores are beginning to demonstrate some tangible utility. For cardiovascular disease, MI-GENES, a 10-year follow ...

Please provide your email address to receive an email when new articles are posted on . More research is needed for preimplantation genetic testing for polygenic disorders. Now, it cannot account for ...