The RFC1 G80A polymorphism is closely associated with higher rates of methotrexate-induced toxicity in pediatric acute lymphoblastic leukemia (ALL), according to a study published in the World Journal ...
In a recent study posted to the medRxiv* pre-print server, researchers reported the association of a single nucleotide polymorphism (SNP) rs9984273 in the interferon-alpha/beta receptor (IFNAR2) gene ...
In this issue, Gryshchenko et al 1 report that a known single nucleotide polymorphism (SNP) in the promoter region of MDM2 is associated with treatment-free and overall survival in chronic lymphocytic ...
Despite global vaccination efforts, COVID-19 continues to pose significant risks, leading to severe complications and fatalities. These risks are driven by disrupted coagulation, impaired fibrinolysis ...
Objective O⁶-methylguanine-DNA methyltransferase (MGMT) removes mutagenic adducts from the O⁶-position of guanine in DNA. Unrepaired O⁶-methylguanines result in G:C to A:T transitions in mutated K-ras ...
An interesting new study published on the preprint server medRxiv* discusses the role of a mucin gene enhancer on the clinical phenotype of the coronavirus disease 2019 (COVID-19), possibly by ...
1982 The Human Polymorphism Study Center, the first academic institution to propose the systematic study of polymorphisms, is founded in Paris. Its primary objective: to make an inventory of all ...
In this issue, Gryshchenko et al 1 report that a known single nucleotide polymorphism (SNP) in the promoter region of MDM2 is associated with treatment-free and overall survival in chronic lymphocytic ...
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