The behaviour of a receptor protein can be influenced by the presence of certain lipids in the membrane it is embedded in.

Misfolded proteins can appear as small aggregates, soluble monomers, or large insoluble inclusion bodies. While the fundamental biophysical mechanisms that cause cytotoxicity are not fully understood, ...

The way proteins move is often what gives them biological activity: they can open, close, twist, and rearrange themselves in ways that allow them to bind to other molecules or perform complex ...

Protein folding helpers such as TRiC and prefoldin (PFD) are crucial for the correct folding of many essential proteins. In a Nature study, researchers from the Max Planck Institute of Biochemistry ...

The strategies biopharmaceutical manufacturers currently use to limit protein misfolding are complex, time-consuming, and generate low yields with only limited scalability. Covalent organic frameworks ...

Adaptor protein (AP) complexes play central roles in intracellular vesicular trafficking by coupling cargo selection to ...

While protein design is experiencing a period of rapid development and advancement, there’s one particularly challenging class of proteins that’s giving researchers a hard time: enzymes. Now ...

The proteins found in nature represent only a tiny fraction of the nearly limitless protein structures that could theoretically exist. By designing proteins de novo—from scratch—scientists can more ...

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert ...