In the cerebral cortex, extrinsic and intrinsic excitatory glutamatergic pathways terminate on principal glutamatergic neurons and local inhibitory GABAergic interneurons. Activation of these pathways ...

Our brain’s memory center bears a sleek design. A peek into living tissue from human hippocampi, a brain region crucial for memory and learning, revealed relatively few cell-to-cell connections for ...

Microglia respond to proteinopathies by changing their shapes and expression profiles in different ways. Here’s one that has been somewhat overlooked: rod-shaped microglia. These long, straight cells ...

The mammalian brain is known to produce mental representations of the spatial environment, known as cognitive maps, that help humans and animals navigate their surroundings. A subpopulation of neurons ...