RNA is key to the dark matter of the genome − scientists are sequencing it to illuminate human health and disease

Researchers are embarking on the RNA equivalent of the Human Genome Project, including sequencing all the chemical ...
New Scientist on MSN

RNA strand that can almost self-replicate may be key to life's origins

Life may have begun when RNA molecules began to replicate themselves, and now we’ve finally found an RNA molecule that is very close to being able to do this ...

Tiny, 45 base long RNA can make copies of itself

These random molecules were fed a collection of three-base-long RNAs, each linked to a chemical tag. The idea was that if a molecule is capable of ligating one of these short RNA fragments to itself, ...

Could the discovery of a tiny RNA molecule explain the origins of life?

One of the greatest mysteries of our planet is how a soup of lifeless chemicals transformed into the first living cell. There are several competing theories about where this happened, from frozen ...

DeepChopper model improves RNA sequencing research by mitigating chimera artifacts

Scientists in the laboratory of Rendong Yang, Ph.D., associate professor of Urology, have developed a new large language model that can interpret transcriptomic data in cancer cell lines more ...
Science Daily

Scientists recover 40,000-year-old mammoth RNA still packed with clues

Researchers have sequenced the oldest RNA ever recovered, taken from a woolly mammoth frozen for nearly 40,000 years. The RNA reveals which genes were active in its tissues, offering a rare glimpse ...
GEN

Cas13’s Intrinsic Targeting of Host RNA Limits Its Utility

Cas13 is capable of intrinsically targeting host RNA in mammalian cells through mechanisms that were not previously understood. Through transcript-specific mechanisms that are independent of the ...
Kaleido Scope

UAB researchers uncover protein SRSF1’s uncommon ability to bind and unfold RNA G-quadruplexes

RNA transcription is the genomic process in which a cell produces a duplicate of a gene’s DNA sequence. Present in both DNA and RNA sequences, a G-quadruplex (GQ) is a structure of four guanine bases ...
Labroots

Odd RNA Caps Reveal a New Kind of Gene Transcription

Scientists have found a new process that happens when an active gene is transcribed from DNA into messenger RNA.. | Cell And ...