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How major nuclear protein complexes control specialized gene regulation in cancer and beyond
Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...
Researchers have discovered how unstructured segments of surface proteins regulate the biological function of a cell. Their study, published in Nature Communications, sheds new light on the interplay ...
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Unveiling the 'functionome': Online resource describes functions of more than 20,000 human genes
A new resource from the Gene Ontology Consortium, a comprehensive encyclopedia of the known functions of all protein-coding human genes, has been completed and released on a new website. For the first ...
A research team led by Zhiping Weng, PhD, and Jill Moore, PhD'18, at UMass Chan Medical School, has nearly tripled the known number of potential ...
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Why promising microbiome therapies rarely work in patients
Addressing the microbiome's translational gap involves understanding biological complexity and developing function-driven, patient-specific interventions.
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