An investigation by researchers from Case Western Reserve University School of Medicine in the US has filled in a missing link between the toxic build-up of proteins in the neurodegenerative condition ...

Support from The Michael J. Fox Foundation for Parkinson’s Research to advance critical research into Parkinson’s disease biology • Nautilus’ ...

New research reveals how Parkinson's spreads from the gut to the brain, with the help of immune cells—offering a new ...

Much of the research into α-synuclein, the major component of Lewy bodies in Parkinson’s and other neurodegenerative diseases, focuses on its role in synaptic vesicles and membranes. But could other ...

More than a decade has passed since researchers led by Dennis Selkoe of Brigham and Women’s Hospital in Boston first reported that when α-synuclein has its druthers, it prefers the company of three ...

Alpha synuclein is a key drug target in Parkinson's Disease with the ability to aggregate into oligomers and fibrils. Research into α-synuclein has rapidly progressed in recent years with a lot of the ...

After three years of study, the researchers found that alpha-synuclein, a protein closely linked to Parkinson’s disease, ...

The study, conducted in mice and published in the Nature journal, identifies a key role of gut macrophages -- a specialised immune cell that kills pathogens -- in the transfer of toxic proteins from ...

In Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy, accumulation of aggregates of abnormally phosphorylated α-synuclein is observed, and these diseases are collectively ...

Serum α-synuclein was found to be increased in children with obesity and type 1 diabetes (T1D), which was linked to the impairment of executive function in these children. A study published in the ...