Two proteins found on the surface of motor neurons in the brain may be essential in the progression of Parkinson’s disease, according to new Yale School of Medicine (YSM) research. Parkinson’s disease ...

Could synucleinopathies start in the kidneys? In the January 23 Nature Neuroscience, scientists led by Zhentao Zhang at Wuhan University, China, report that, in people with Parkinson’s and Lewy body ...

Proteins form the building blocks of life, but when they form unusual clumps inside the brain, they raise an alarm that ...

Alpha-synuclein oligomers play a key role in the development and progression of the disease and, therefore, are promising therapeutic and diagnostic targets, particularly in the early stages of the ...

For synucleinopathies, which include Parkinson’s disease, multiple system atrophy, and dementia with Lewy bodies, scientists currently have no way to slow the underlying disease progression. Many ...