Mammalian hosts coordinate various cell death pathways as part of the immune defense system against pathogens including Mycobacterium tuberculosis (Mtb), which causes tuberculosis featuring lung ...

A histone acetylome-wide associations study (HAWAS) performed in immune cells from patients with active Mycobacterium tuberculosis infection versus those from healthy controls, has for the first time ...

New observations of the early stages of tuberculosis infection may turn scientists' understanding of the bug's pathogenesis on its head: clumps of immune cells, called granulomas, long thought to ...

In 2021, a global tuberculosis vaccine research and development roadmap proposed a series of actions to accelerate the development of new, effective, and affordable vaccines that are urgently needed ...

Biology students and faculty members from The University of Texas at El Paso have discovered a new target for tuberculosis drug development. Their study recently was published in the Journal of ...

A team of United States-based scientists recently conducted a study to evaluate the effect of Mycobacterium tuberculosis infection on the pathogenesis of severe acute respiratory syndrome coronavirus ...

Disseminated tuberculosis is a type of tuberculosis (TB) where mycobacteria spread via blood to other organs beyond the lungs. It can cause severe multiple-organ damage in the absence of early ...

Mycobacterial diseases, including tuberculosis (TB), leprosy, and non-tuberculous mycobacterial (NTM) infections, continue to impose a substantial global ...

Tuberculosis remains a major global health threat, and symptom-based case detection fails to interrupt community transmission.1 Nearly half of tuberculosis cases are missed by current strategies, and ...