Nature

Risk assessment in solitary fibrous tumors: validation and refinement of a risk stratification model

Solitary fibrous tumors are mesenchymal neoplasms showing fibroblastic differentiation, and characterized by a recurrent intra-chromosomal paracentric inversion involving the long arm of chromosome 12 ...
Risk

Performance validation of representative sample-balancing methods in loan credit-scoring scenarios

Data sets used to construct a credit-scoring model are always imbalanced in the real world, leading to the recognition ability of the model becoming biased toward the majority and low-risk samples and ...
ascopubs.org

Hospitalization Risk During Chemotherapy for Advanced Cancer: Development and Validation of Risk Stratification Models Using Real-World Data

Key Objective To develop and validate an approach for identifying patients at increased risk for hospitalization after initiation of chemotherapy for advanced cancer. Knowledge Generated We describe ...
ascopubs.org

Derivation and Validation of a Clinical Risk Assessment Model for Cancer-Associated Thrombosis in Two Unique US Health Care Systems

A Clinical-Genetic Risk Score for Predicting Cancer-Associated Venous Thromboembolism: A Development and Validation Study Involving Two Independent Prospective Cohorts Using retrospective data from ...
Business Wire

aeSolutions to Present Three-Part Webinar on Trustworthy Risk Assessments, Quantitative Risk Assessment (QRA), and Data Validation in Process Safety

GREENVILLE, S.C.--(BUSINESS WIRE)--aeSolutions, a consulting, engineering and systems integration company, will be presenting a three-part webinar series on applying risk assessments in the ANSI/ISA ...
National Academies of Sciences%2c Engineering%2c and Medicine

Building Confidence in New Evidence Streams for Human Health Risk Assessment: Lessons Learned from Laboratory Mammalian Toxicity Tests

Suggested Citation: "5 Issues in Developing a Scientific Confidence Framework for NAMs." National Academies of Sciences, Engineering, and Medicine. 2023. Building Confidence in New Evidence Streams ...
Risk

How accurate is the accuracy ratio in credit risk model validation?

The receiver operating curve and the cumulative accuracy profile visualize the ability of a credit scoring model to distinguish defaulting from nondefaulting counterparties. These curves lead to ...
PharmTech

Evolution of Analytical Procedure Validation Concepts: Part II– Incorporation of Science and Risk-based Principles in ICH Q14 and Q2(R2) Guidelines

No additional expectations or mandated requirements are expected in Q14, Q2(R2) and USP <1220>. The minimal approach can still be used. Q14 and Q2(R2) are consistent with the principles described in ...
Business Wire

CyberGRX Continues to Challenge Traditional Assessments By Introducing In-Platform Auto Validation

DENVER--(BUSINESS WIRE)--CyberGRX, provider of the world’s first and largest global cyber risk exchange, today announced the introduction of in-platform Auto Validation, a new feature that speeds up ...
CMAJ

Predicting death in home care users: derivation and validation of the Risk Evaluation for Support: Predictions for Elder-Life in the Community Tool (RESPECT)

BACKGROUND: Prognostication tools that report personalized mortality risk and survival could improve discussions about end-of-life and advance care planning. We sought to develop and validate a ...