Endothelial barrier function requires the adhesive activity of VE-cadherin and claudin-5, which are key components of adherens and tight endothelial junctions, respectively. Emerging evidence suggests ...
Figure 2: VE-PTP dephosphorylates VEGFR2 in a Tie2-dependent manner. The requirement for Tie2 in VE-PTP dependent dephosphorylation of VEGFR2 was further demonstrated by silencing either VE-PTP or ...