News-Medical.Net on MSN

Newly discovered survival pathway explains stubborn EGFR-driven lung cancers

Scientists from A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB) have identified why certain lung cancer cells ...
ascopubs.org

Analysis of EGFR pathway mediators in KRAS wild-type primary tumors is not representative of their status in related metastases.

New insights to gene expression signatures from primary FFPE tumors for the prediction of response to cetuximab in KRAS and BRAF wild-type colorectal cancer (CRC). Background: KRAS mutated CRC ...
The American Journal of Managed Care

Edward Arrowsmith, MD, MPH, Discusses EGFR Exon 20 Insertion+ NSCLC, How Knowledge Fits Into Pathways

Edward Arrowsmith, MD, MPH, medical director for clinical pathways for OneOncology, discussed treatment challenges in EGFR Exon 20 insertion+ non-small cell lung cancer (NSCLC) and best practices in ...
Targeted Oncology

FDA Accepts BLA for Ivonescimab in Pretreated EGFR-Mutated NSCLC

Ivonescimab's BLA acceptance is a milestone for PD-1/VEGF bispecific antibodies in the U.S., potentially transforming ...
Lupus Science & Medicine

Trajectories of long-term eGFR and proteinuria in lupus nephritis: a real-world biopsy-proven cohort study

Background The long-term trajectories of estimated glomerular filtration rate (eGFR) and their relation to early proteinuria ...
ascopubs.org

Clinical relevance of insulin regulatory pathways in non-small cell lung cancer (NSCLC) progression.

Impact of EGFR and KRAS mutations on survival in 1,000 patients with resected lung adenocarcinoma. Background: Insulin and insulin-like growth factors are key regulators of normal metabolism and ...
Everyday Health on MSN

Decoding your IGAN lab results: Understanding EGFR and UPCR, and predicting future kidney health

Understanding eGFR and uPCR is vital for managing IgA nephropathy to predict kidney health, guide treatment, and work ...