Organic synthesis is based on carbon-carbon bond formation. Aldol condensation is one of the key reactions, forming a new β-hydroxy carbonyl compound through the reaction of two carbonyl compounds.
The protocol for the preparation of boron enolates and their subsequent reaction with aldehydes is described, providing convenient access to β-hydroxy ketones in good yields and with high ...
The catalytic aldol condensation reaction represents a pivotal method for synthesising acrylic acid through the coupling of simple carbonyl compounds such as acetic acid, formaldehyde and methanol.
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