A wave of spatial transcriptomics studies has produced gene-expression atlases that span entire organs and whole organisms, from mouse embryos to the roundworm C. elegans to 31 human tissues. These ...

A protein called SLIT3 splits into two parts, with each piece guiding the growth of blood vessels and nerves inside brown fat. These structures allow the tissue to pull in nutrients and rapidly ...

The new findings, including how SLIT3 splits into two parts and interacts with receptors to shape nerve and blood vessel networks, point to several potential targets for future treatments.

Emerging evidence links popular weight-loss drugs to lower cancer rates, but are these effects real, or simply a reflection of better metabolic health?

Typically, mice, like, humans, have a system that prevents the mother’s immune system from attacking a developing offspring, even though that offspring’s cells do not have the same genetic material as ...

Scientists have uncovered a surprisingly large reserve of “silent synapses” in the adult brain—unused neural connections that can be rapidly activated to store new memories.

If you want to know more about how the human brain matures and changes over time, you can now consult the first comprehensive atlas that maps brain organization from infancy all the way through to ...

APOE4 drove sex-specific changes in meningeal immunity, lymphatic drainage, brain lipids, neuroinflammation, and cognition in mouse models, with females showing greater inflammatory and cognitive ...

Gut microbiome changes may drive age-related memory loss via inflammation and disrupted brain signaling, but interventions in mice show this process can be reversed.

The first PC game to stick in Nelson Jr's brain was Sid Meier's Pirates!, the 2004 remake of the 1987 piracy simulator. "I think [it's] one of the most perfect examples of what a ...