Immunoglobulin A (IgA) nephropathy is an autoimmune disease characterized by the deposition of circulating IgA-containing immune complexes (IgA-ICs) in the glomerular mesangium, leading to mesangial ...

Q16W dosing interval; Furthermore, nearly 60% of the participants held the potential to extend the dosing interval to ...

Rheumatoid arthritis is a chronic autoimmune disease that affects millions of people worldwide. This disease prompts the ...

For years, patients with C3G and IC-MPGN had few options to stop the progression toward kidney failure. Now a new class of ...

Biocodex Introduces Fullify™, a First-of-Its-Kind Precision Probiotic Clinically Shown to Activate the Gut-Brain Pathway to Support Appetite Management Backed by Over a Decade of Research, Fullify ...

Sickle cell disease can lead to a severe complication known as acute chest syndrome (ACS), but the underlying mechanisms are not well understood. A new study by Mass General Brigham investigators ...

Dysregulated complement pathways are linked to progression from iAMD to advanced AMD, including NVAMD and GA. Higher systemic levels of C4, C4b, and a reduction in C3 are associated with increased ...

SEATTLE--(BUSINESS WIRE)--Omeros Corporation (Nasdaq: OMER) today announced that the U.S. Food and Drug Administration (FDA) has accepted for review the resubmission of the Biologics License ...

The Complement System (CS) comprises three catalytic pathways that can be activated by specific immune triggers. However, within the tumor microenvironment (TME), CS intracellular components, recently ...

Please provide your email address to receive an email when new articles are posted on . A protein known as granzyme K was recently shown to be a driver of inflammation by activating the complement ...